Monday, December 31, 2012

'Saint of Death' gathers followers in Mexican town

Lined up inside a dark-black painted building in Ciudad?Ju?rez, Mexico, worshippers of La Santa Muerte wait their turn to place their rolled-up paper prayers at the feet of a 5-foot tall statue of an idolized female skeletal figure. She is draped in a white, laced cloak and holds a small globe in one hand, and a tall wooden scythe in the other.

Many of the Santa Muerte statues started popping up in this city around 2009, when drug-related violence began to ravage this border town. More than 10,000 people have been killed in Ciudad?Ju?rez?alone since 2007, when Mexico?s outgoing President Felipe Calder?n?first declared war on the country?s drug cartels. The murder rate earned Ciudad?Ju?rez?the title of murder capital of the world for a while.

Santa Muerte statue looks over prayer room during vigil. (Photo by Alex Pe?a)

Santa Muerte statue looks over prayer room during vigil. (Photo by Alex Pe?a)

Followers recognize La Santa Muerte as an iconic figure of prayer for those looking for protection. The Catholic Church in Mexico denounces the worship as a cult.

The origins of Santa Muerte worship is debated, but many believe it came from the ancient Aztecs and their worship of death. The modern image of Santa Muerte is believed to have surfaced in the mid-20th?century in poor areas of Central Mexico. Now, Santa Muerte can be found throughout all of Mexico, the border, and even some parts of the United States.

Yolanda Salazar inside her prayer room. (Photo Alex Pe?a)

Yolanda Salazar inside her prayer room. (Photo Alex Pe?a)

?You can ask the Santa Muerte for many things,? said Yolanda Salazar, self-proclaimed priestess of the Santa Muerte cult in Ciudad Juarez.

?Here in?Ju?rez, people pray for protection, but also health, and for love. What?s important is it comes from the heart. If your intentions are true, it will help you,? she said.

Salazar lives in and runs this particular sanctuary, which is located in the heart of the city, just a drive of a few minutes from the border with the United States. It?s believed there are many makeshift sanctuaries and Santa Muerte altars in?Ju?rez, but Salazar?s is public, and the most popular.

She said she had just a handful of followers in 2010, when she first opened her Santa Muerte sanctuary, which consists of perhaps 100 or more small and large statues of Santa Muerte. This year, her weekly prayer vigils to the Santa Muerte draw in a crowd similar to the size of a Catholic Mass.

Sign telling Santa Muerte believers where to place their money for good luck economically. (Photo by Alex Pe?a)

Sign telling Santa Muerte believers where to place their money for good luck economically. (Photo by Alex Pe?a)

On this particular night, her vigil resembled more of a Mexican fiesta than an underground worship of death. Mariachi music flooded out into the street, and the 25 or more worshipers ate and danced while the others went inside to make their offerings.

?This has always existed here, but people were timid about professing their belief. They were afraid to be judged by society,? Salazar said. ?But now, a lot of us don?t really care what society thinks.?

According to Salazar, the violence in the city has drawn many followers to her sanctuary, searching for protection that neither the church nor their government can give them.

?Now that it?s come to light, I would say that 40 percent of the people in Juarez believe in Santa Muerte,? she said. ?Still, not all are professing it.?

In Mexico, a traditionally Catholic society, the worship of a deity that isn?t recognized by the Catholic Church usually?means?an association to criminal organizations. Members of drug cartels, commonly referred to as narcos, have long been followers of the Santa Muerte.

Little girl looks into glass window lined with life size statues of La Santa Muerte. (Photo by Alex Pe?a)

Little girl looks into glass window lined with life size statues of La Santa Muerte. (Photo by Alex Pe?a)

Narcos make offerings to the icon in return for protection in their illicit activities. In some rare and very brutal cases, the offerings have consisted of human body parts.

Eight people were arrested in northern Sonora state in March of this year after they were accused of killing two ten-year-old boys and a woman in ritual Santa Muerte sacrifices.

Salazar said that this type of worship is not the ?true cult? of La Santa Muerte.

?This is not exclusively for the narcos,? she said. ?Even police go to her for protection. Even they realize how powerful she is.?

The Catholic Church in Mexico has consistently denounced the worship of such a deity, but it cannot deny the rise in adoration for such figures in Mexico?s violent border towns.

Rev. Felipe de Jes?s Ju?rez,?head priest at Our Lady of the Sacred Heart Catholic Church in CD.?Ju?rez, says the belief of Santa Muerte arrived in Ciudad?Ju?rez?around 2009 and 2010, at the height of the violence. Though the murder rate has dropped dramatically, the culture of death has not.

Mix of flowers, ginger, and other ingredients being offered as a sacrifice to La Santa Muerte inside of Sanctuary. (Photo by Alex Pe?a)

Mix of flowers, ginger, and other ingredients being offered as a sacrifice to La Santa Muerte inside of Sanctuary. (Photo by Alex Pe?a)

?We are all exposed to this new cultural situation. Here in the border we see a lot of different types of beliefs,??Ju?rez?said. ?This started with people who don?t have a good moral base. They are grabbing death, putting a cloak on it, and making it a saint. But it?s not a saint; it?s death.?

In the case of Santa Muerte, once followers pray to her, they believe she will grant them favors, but they must repay her.

?If they don?t, they believe they will be punished,??Ju?rez?said. ?So many live in fear.?

He said he opposes such a practice because he believes the grace of God is free.

Nonetheless,?Ju?rez?recognizes the power of Yolanda Salazar and her followers of this growing cult in his city.

?This woman, a self-proclaimed high priest who started out of her house, now has a full building with a sanctuary,? he said. ??The devotion in Mexico is very strong.?

Candles lit for prayer vigil inside Santa Muerte Sanctuary. (Photo by Alex Pe?a)

Candles lit for prayer vigil inside Santa Muerte Sanctuary. (Photo by Alex Pe?a)

And nowhere is the diversity of Santa Muerte worship more prevalent than inside the gates of a Salazar prayer vigil. Little boys and girls hold flowers and candles as offerings; their parents write the prayers on small sheets of paper.

All while a group of teenagers stand and chat near the door, waiting their turn to enter and place their own prayers.

?I feel a lot of security,? said Alexia Varaza, 20, a follower of Santa Muerte. ?I?ve had a lot of luck with La Santa Muerte. She gives me strength.?

Varaza?s mother and father are believers in the cult, but the rest of her family is skeptical.

?That stuff?s for sicarios ? for killers!? said Varaza,?explaining what her family thinks of the cult vigils she attends every weekend.

?That?s not what it is for me. I just tell them I?m a student, and I need the good luck!?

Whether for sicarios or students, Salazar?s doors are open 24/7 to people searching for protection in a city saturated with violence.

?The real cult, our cult, is to go out and profess the goodness of La Santa Muerte,? Salazar said. ?That?s why I opened the sanctuary.?

Salazar has plans to open another Santa Muerte sanctuary next year, with the expectation that her following will continue to grow as massively as during the past year. ?She certainly will be praying to her beloved Santa Muerte for that to happen.

Alex Pe?a is a freelance foreign correspondent currently covering Ciudad Juarez, Mexico. Previously, Pena was based in Nairobi, Kenya covering East Africa for Voice of America TV, and has also filed stories from the Middle East, including the border of Jordan and Syria. He graduated from the journalism program at Florida Gulf Coast University in December 2011.

Source: http://nbclatino.com/2012/12/31/la-santa-muerte-cult-sees-major-growth-in-mexican-border-town/

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The factor that could influence future breast cancer treatment -Breast ...

? Breast Cancer news ? Dec 29, 2012

Australian scientists have shown in the laboratory how a ?transcription factor? causes breast cancer cells to develop an aggressive subtype that lacks sensitivity to estrogen and does not respond to known anti-estrogen therapies. The research, which has significant implications for breast cancer treatment, is published December 27 in the open access journal PLOS Biology.

Transcription factors are molecules that switch genes on or off. In this case, the transcription factor known as ?ELF5? inhibits sensitivity to estrogen very early in the life of a breast cancer cell. In 2008, Professor Chris Ormandy from the Garvan Institute of Medical Research in Sydney, Australia, showed that ELF5 was responsible for the development of breast progenitor cells into the estrogen-receptor-negative cells that produce milk in the breast during pregnancy.

In the current study, a team led by Ormandy in collaboration with Drs Maria Kalyga and David Gallego-Ortega, has shown that the same molecular decision occurs in breast cancer and that ELF5 has the ability to change an existing tumour into an estrogen-insensitive tumour.

?This work tells us that cancers which become refractory to anti-estrogen treatment often do so by elevating their levels of ELF5 and becoming functionally estrogen receptor negative,? said Ormandy.

The team has also described the genetic mechanisms by which ELF5 opposes the action of estrogen, and has shown that it is possible to alter the subtype of breast cancer by manipulating ELF5 levels in cancer cells in the laboratory.

?This raises the therapeutic option of manipulating ELF5 levels to treat breast cancer. As ELF5 is intracellular, this could possibly be done with small molecule therapies that penetrate cells and target protein-to-protein interactions, or with small inhibitory RNAs. There is also the possibility of testing ELF5 levels in tumours to predict response to treatment and therefore guide treatment decisions.?

?Our key discovery here is that by simply manipulating one transcription factor we can change the subtype of breast cancer.?
###

Funding: This work was funded by The National Health and Medical Research Council of Australia, New South Wales Cancer Council, Cancer Institute New South Wales, Banque Nationale de Paris-Paribas Australia and New Zealand, RT Hall Trust, Australian Cancer Research Foundation, Prostate Cancer Foundation Australia, Cure Cancer Foundation Australia, Breast Cancer Campaign UK, and the National Breast Cancer Foundation. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Competing interests: The authors have declared that no competing interests exist.

Citation: Kalyuga M, Gallego-Ortega D, Lee HJ, Roden DL, Cowley MJ, et al. (2012) ELF5 Suppresses Estrogen Sensitivity and Underpins the Acquisition of Antiestrogen Resistance in Luminal Breast Cancer. PLoS Biol 10(12): e1001461. doi:10.1371/journal.pbio.1001461

CONTACT:
Christopher Ormandy
Garvan Institute
Sydney, AUSTRALIA

###

Bryan Ghosh

44-122-344-2837
Public Library of Science

Provided by ArmMed Media




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Source: http://www.health.am/cr/more/influence-future-breast-cancer-treatment/

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Taco Bell Pregame Press Pass: Coach Arians signing autographs for fans Pregame....

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Saving Mackenzie Rivers

Saving Mackenzie Rivers

In the year 2062, humans live in a wasteland under strict policy of the dictator. Recently, a gang of robots from the past with artificial intelligence and no idea what happened has been spotted, and they might hold the key to a better life.

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Junior Dos Santos Vs. Cain Velasquez Preview: UFC 155, Where To Watch Live Online Stream, Betting Odds, Undercard, Tale Of The Tape

Junior Dos Santos puts his UFC Heavyweight title on the line Saturday night against Cain Velasquez at the MGM Grand Arena in Las Vegas.

Billed as one of the top rematches in recent years, Dos Santos originally captured his belt from Velasquez in November of last year with a vicious first round knockout in the first 1:04.

Velasquez didn?t fold after his first career loss, and took on and was victorious over the legendary Antonio Silva with a TKO in May. After 11 career fights, the 30-year-old is 10-1 with nine KOs.

Dos Santos, a native of Brazil, has a reputation as one of the strongest and most devastating punchers in all of UFC, evidenced by his 11 career KOs.

The other top fights, as well as the undercard, are listed below. Fights are subject to change.

The live event will start at 7 p.m. EDT, and if you can?t purchase the PPV at out home there are several ways to watch undercards and the main event live online by going to UFC?s main website.

Main Card

Junior dos Santos

Age: 28

Height: 6?4?

Weight: 239 lbs.

Reach: 77?

Record: 15-1, 11 KOs

Cain Velasquez

Age: 30

Height: 6?1?

Weight: 240 lbs.

Reach: 77?

Record: 10-1, 9 KOs

Betting Odds: Dos Santos -200

?

Jim Miller vs. Joe Lauzon

Tim Boetsch vs. Constantinos Philippou

Yushin Okami vs. Alan Belcher

Chris Leben vs. Derek Brunson

?

Preliminary Card

Brad Pickett vs. Eddie Wineland

Erik Perez vs. Byron Bloodworth

Melvin Guillard vs Jamie Varner

Todd Duffee vs Philip De Fries

John Moraga vs Chris Cariaso

Max Holloway vs Leonard Garcia

Source: http://www.ibtimes.com/junior-dos-santos-vs-cain-velasquez-preview-ufc-155-where-watch-live-online-stream-betting-odds

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10 Secrets to a Fit Family | FatDrop

It?s no secret that many parents and their children are overweight. These 10 simple ?secrets? can help you change your family?s lifestyle so that you can all become fit and healthy.

1) Eat Whole Grain Foods

Processed and refined grains, such as white bread, white rice, cereal, pasta, and other foods made with white flour have a high glycemic index, low amounts of fiber, and less vitamins and minerals as foods made with whole grains. Making the switch to whole grain foods, including whole wheat bread, whole grain pasta, brown rice, and cereals made with whole grains, are an easy and healthy way to make your family?s diet more nutritious.

2) Limit Soda and Fruit Drinks

Soda and fruit drinks have low nutritional value and a lot of calories. At about 150 calories per 12 ounce serving, your kids will gain an extra pound about every 3 weeks if they drink just one can of soda each day.
Cutting back or eliminating soda, fruit drinks, and even fruit juice, can be a good way to get rid of a lot of extra calories and leave room for your kids to eat more nutritious foods.

3) Eat More Fruits and Vegetables

Most children don?t eat enough fruits and vegetables and that usually means that they are eating other less nutritious foods. With a high fiber content and lots of vitamins and minerals, fruits and vegetables are an important part of a healthy diet. And because they have lots of water in them, eating fruits and vegetables can help you to feel full and satisfied so that you don?t overeat.

4) Eat More Foods with Calcium

A common mistake people make when trying to lose weight is that they stop drinking milk, eating cheese and yogurt. Calcium is important to build healthy bones and to help you lose weight. You should encourage your kids to drink low-fat milk, eat portioned amounts of cheese and yogurt to help lose weight and maintain a healthy weight.

5) Be More Active

Everyone knows that part of the cause of the current obesity epidemic is that people are much less active then they used to be. Getting kids involved in organized activities, which can be either team or individual sports, and cutting back on the amount of time in front of the TV, computer and playing video games will burn calories and improve fitness levels.

Family activities are also a good way to be more physically active. Even simple things, like walking across a parking lot, using stairs, and going for short family walks or bike rides, can make a big difference.

6) Know Where Calories Come From

While you don?t necessarily need to do daily calorie counts, keep a diary of what your family eats for a few days can help you see where extra calories are coming from. Are your kids overweight because of the calories they get from a bedtime snack or those two glasses of Kool Aid or soda he drinks? Or maybe because his portion sizes are too large?

If you know where your kids? calories are coming from, you will know where to make changes and how you can cut back, especially on foods that have a lot of empty calories.

7) Learn About Carbs

Carbs get a bad wrap, especially with all of the proponents of high protein diets, like the Atkins and South Beach Diet. Not all carbs are created equal. While it is a good idea to avoid foods that have refined such as white bread, foods made with white flour, and foods and beverages sweetened with sugar, other carbs should be part of a balanced diet.

Instead of avoiding all carbs, just learn about how to choose foods with ?good? carbohydrates, which includes fruits, vegetables, beans, and whole grain foods.

8) Learn About Fats

Like carbs, there are ?good? and ?bad? fats. Instead of making the mistake of trying to stick to a low fat diet, and simply substituting other foods that are often just as high in calories, you should eat foods that have ?good? fat in them. This includes foods with polyunsaturated and monounsaturated fats. On the other hand, you should avoid saturated fats and trans fats.

9) Choose Healthy Meals when Eating Out

Even if your family eats healthy at home, if you eat super-sized fast food meals a few times a week, they are probably still at risk for becoming overweight. If you eat out a lot, review the nutritional facts of the restaurant?s menu and watch your portion sizes. Calories and fat quickly adds up when eating out!

10) Stay Motivated!

Most people know what they need to do to be healthier however, eating healthy and exercising is not easy.?? Education about the specifics of a healthy diet, getting the whole family involved, and setting goals, can help your family stay healthy and fit.? Hire a personal trainer or seek the counsel of a dietitian to keep you on the healthy track.

Source: http://fatdrop.info/10-secrets-to-a-fit-family/

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Junior Dos Santos vs. Cain Velasquez Results: Round by Round Recap and Analysis

Saturday night at UFC 155, Junior dos Santos puts his heavyweight title on the line against challenger and former champ Cain Velasquez.

Dos Santos (15-1, 9-0 UFC) will try to defend his belt for the second time. Velasquez (10-1, 8-1 UFC) hopes to reclaim the title he lost to Dos Santos in November 2011, when the two fought on the inaugural UFC on Fox card.

Read on for real-time, round-by-round analysis as the action unfolds.?

Source: http://bleacherreport.com/articles/1461863-junior-dos-santos-vs-cain-velasquez-results-round-by-round-recap-and-analysis

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Saturday, December 29, 2012

4 dead in Moscow airliner crash

MOSCOW (AP) ? A passenger airliner careered off the runway at Russia's third-busiest airport and partly onto a highway while landing on Saturday, broke into pieces and caught fire, killing at least four people.

Officials said there were eight people aboard the Tu-204 belonging to Russian airline Red Wings that was flying back from the Czech Republic without passengers to its home at Vnukovo Airport.

Emergency officials said in a televised news conference that four people were killed and another four severely injured when the plane rolled off the runway into a snowy field and partly onto an adjacent highway, then disintegrated. No collisions with vehicles on the major, multilane highway were reported.

The plane's cockpit area was sheared off from the fuselage and the tail section partly torn away.

The crash occurred amid snow and winds gusting up to 15 meters a second (30 mph), but other details were not immediately known. A spokesman for Russia's top investigative agency, Vladimir Markin, said initial indications were that pilot error was the cause.

The state news agency RIA Novosti cited an unidentified official at the Russian Aviation Agency as saying another Red Wings Tu-204 had gone off the runway at the international airport in Novosibirsk in Siberia on Dec. 20. The agency said that incident, in which no one was injured, was due to the failure of the plane's engines to go into reverse upon landing and that its brake system malfunctioned.

On Friday, the Aviation Agency sent a directive to the Tupolev company's president calling for it to take urgent preventive measures.

The plane that crashed Saturday took off from Pardubice airport in the Czech Republic. Jan Anderlik, the director of the company that operates the airport, told Czech public television that the plane underwent a regular technical check before takeoff and no problems were discovered.

Prior to Saturday's crash, there had been no fatal accidents reported for Tu-204s, which entered commercial service in 1995. The plane is a twin-engine midrange jet with a capacity of about 210 passengers.

The Red Wings airline is one of the holdings of Russian billionaire Alexander Lebedev, who also owns the British newspapers The Independent and the Evening Standard.

Vnukovo, on the southern outskirts of Moscow, is one of the Russian capital's three international airports.

___

Vladimir Isachenkov in Moscow, and Karel Janicek in Prague, Czech Republic, contributed to this story.

Source: http://news.yahoo.com/4-dead-moscow-airliner-crash-152110693--finance.html

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How to fix your cholesterol without prescription drugs

(NaturalNews) Though many people still do not realize this, our bodies actually need cholesterol in order to survive, as the brain and central nervous system rely on this important fat to both protect the integrity of neurons and promote proper neural communication and function. But sometimes cholesterol fails to properly assimilate where it needs to go inside the body, or the size and density of cholesterol particles get out of whack due to an underlying health condition or poor diet and lifestyle, which is what commonly gets attributed to chronic health problems such as heart disease and metabolic syndrome.

The tendency among conventional practitioners, of course, is to address this chronic cholesterol imbalance by trying to artificially lower it, as "high cholesterol" has become a popular buzz phrase for ill health, and therefore it must be reduced by whatever means possible. But like all other drug-based approaches to disease, this focused, cholesterol-lowering approach fails to address the underlying causes of high cholesterol, which include things like insulin resistance and diabetes. In fact, high cholesterol itself is actually a symptom of another underlying health condition, rather than a condition in and of itself.

"The singular focus on treating cholesterol as a means to prevent heart attacks is leading to the deaths of millions of people because the real underlying cause of the majority of heart disease is not being diagnosed or treated by most physicians," wrote practicing physician Dr. Mark Hyman, M.D., in a 2011 piece on cholesterol for The Huffington Post. "Abnormal cholesterol levels are just a downstream problem that is mostly a result of 'diabesity' or the continuum of blood sugar and insulin imbalances that range from pre-diabetes to full-blown end stage diabetes."

What this means is that simply popping the latest cholesterol drug will do little, if anything, to actually fix your cholesterol problems. In fact, Dr. Hyman explains that cholesterol drugs, even if they initially appear to bring cholesterol levels back into a healthy range, actually lead to more deaths from heart attack and heart disease in the long run because they treat the symptom rather than the disease, and create harmful side effects in the process. In the end, if dietary and lifestyle changes are not instigated, people with disease-induced high cholesterol will face the same ill outcomes of heart disease and death, regardless of whether or not they take cholesterol drugs.

"Drugs don't treat the underlying causes of chronic illness," added Dr. Hyman in his report. "It is not our genes which haven't changed much in 20,000 years, although they may predispose us to environmental and lifestyle triggers of illness. The causes of chronic disease are rooted in what we eat, how much we move, how we face stress, how connected we are to our communities and toxic chemicals and metals in our environment."

So what can you do to practically address your cholesterol issues in such a way as to also address the underlying health conditions that are causing it? The first thing Dr. Hyman suggests is to 1) get properly tested for cholesterol, which includes testing for cholesterol particle size and density. Healthy circulating cholesterol should be "light and fluffy," he says, rather than small and dense. You can ask your doctor specifically for such a test, which Dr. Hyman says is available through popular testing companies like Labcorp and LipoScience.

If it is determined that your cholesterol particles are too small and dense, the next step is to 2) test for metabolic syndrome. Dr. Hyman has created a helpful list of five steps you can take to determine whether or not you have this under-diagnosed condition, and these steps can be found towards the bottom of the following article: http://www.huffingtonpost.com

High cholesterol can also be indicative of a chronic inflammation problem, which means you may need to 3) make significant and potentially drastic dietary changes to correct it. Oddly enough, eating low-cholesterol and low-fat foods, including refined vegetables oils rather than saturated fats, is a common cause of chronic inflammation. Health and fitness expert Charles Poliquin explains in the following article more of the specifics as to how inflammation is actually the culprit in heart disease rather than high cholesterol: http://www.charlespoliquin.com

4) Reducing your carbohydrate intake and boosting your complex protein intake is another great way to not only quell any inflammation that might be linked to your high cholesterol, but also to feed your body the nutrients it needs to remedy metabolic syndrome and diabetic conditions. This means 5) eliminating processed flours and refined sugars, and 6) replacing them with proteins and healthy fats from grass-fed meats, nuts and other whole foods. Eating more coconut oil, grass-fed butter, raw milk, and trace mineral-rich sea and earth salt can also help address the underlying causes of high cholesterol.

Sources for this article include:

http://www.huffingtonpost.com

http://www.nativeremedies.com

http://www.charlespoliquin.com

http://www.psychologytoday.com

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?people have commented on this article.

Source: http://www.naturalnews.com/038489_high_cholesterol_prescription_drugs_natural_remedies.html

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First genome sequence of Chinese plum provides important resource for fruit improvement

Dec. 27, 2012 ? A Chinese research team, led by Beijing Forestry University, BGI, Beijing Lin Fu Ke Yuan Flowers Co., Ltd, and other institutes, has completed the first genomic sequence of Prunus mume, known as mei. This work is extremely important for the deeper understanding of Rosaceae evolution and provides an invaluable resource for the improvement of fruit trees.

The latest study was published online December 27 in Nature Communication.

As one of the longest-lived flowering fruit trees, the P. mume was domesticated in China more than 3,000 years ago. It belongs to Rosaceae, the third most economically important plant family in temperate regions, and is characterized by high nutrition, medical value, and tolerance to low temperature in winter. Writers and artists have extolled the beauty of its flowers, and the blossom is considered to be the symbol of Chinese national spirit. The availability of P. mume genome will open a new way for better decoding the mysteries of this fascinating tree.

The plantation technique that makes P. mume so diverse--the artificial grafting--also makes their genomes difficult to assemble. In this study, researchers sequenced the genome of P. mume, a wild species from Tibet in China, using a robust approach integrated with next-generation sequencing (NGS) and whole-genome mapping (WGM) technologies. Then they constructed a high-density genetic map by applying restriction-site-associated DNA (RAD) marker strategy that further improves the quality of the genomic reference. Through all the efforts, researchers yielded the ~237Mb P. mume reference genome.

The poor phylogenetic resolution of the Rosaceae suggests rapid evolution within the family. In this study, the evolutionary analysis of P. mume genome demonstrated that there was no recent whole-genome duplication (WGD) event happened after the differentiation between P. mume and Malus x domestica (apple). However, the triplicated genomic arrangement was found in the P. mume genome by paleo-history analysis in Prunus.

Supported by the genomic data of apple and strawberry (Fragaria vesca), researchers successfully reconstructed nine ancestral chromosomes of Rosaceae family, and analyzed the chromosome fusion, fission and duplication history in three major subfamilies, including genera Prunus, Malus and Fragaria. Through analysis, they hypothesized that at least 11 fissions and 11 fusions occurred in P. mume from the nine common ancestral chromosomes. For apple, at least one WGD and five fusions took place to reach the 17-chromosome structure, compared with 15 fusions for strawberry to affect the 7-chromosome structure.

P. mume is one of the first trees that bloom in early spring, blooming even below 0?. In this study, researchers investigated the genetic characteristics underlying the mechanisms related to acclimate to cold weather and release itself from dormancy. They found that dormancy-associated MADS-box transcription factors (DAM) family and C-repeat-binding transcription factors (CBF) were two important factors related with flowering dormancy.

As the saying goes, "Plum blossom incense from the cold weather," P. mume always has a special fragrance in winter. To understand its mechanism of floral scent, researchers identified a series genes related to the biosynthesis of volatile compounds, such as benzyl alcohol acetyltransferase (BEAT) gene. They supposed the expansion of the BEAT gene family might increase the content of benzyl acetate and therefore induces the special fragrance of P. mume.

The disease resistance related-genes may benefit the future breeding improvement. In this study, researchers found many related genes expanded tremendously in the P. mume genome, such as leucine-rich repeat receptor-like kinase (LRR-RLK) genes, the nucleotide-binding site-coding resistant gene (NBS-coding R gene), and pathogenesis-related (PR) gene families. It was reported that PR proteins could mediate plant defence against pathogenic constraints and the general adaptation to stressful environments. Most PR gene families in P. mume were expanded notably especially PR10, suggesting their expansion might be related to the response of P. mume to salt, drought and fungal infection in roots and leaves.

Wenbin Chen, Project Manager of BGI, said, "The P. mume genome lays a solid foundation for identification of important economic traits, and provides a valuable resource for P. mume breeding and other Rosaceae species studies. The work here also brings a new approach for further exploring the biosynthesis of floral scent and regulation mechanism of early blooming in endodormancy, and other comparative genomics studies on Rosaceae species."

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Story Source:

The above story is reprinted from materials provided by BGI Shenzhen, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Qixiang Zhang, Wenbin Chen, Lidan Sun, Fangying Zhao, Bangqing Huang, Weiru Yang, Ye Tao, Jia Wang, Zhiqiong Yuan, Guangyi Fan, Zhen Xing, Changlei Han, Huitang Pan, Xiao Zhong, Wenfang Shi, Xinming Liang, Dongliang Du, Fengming Sun, Zongda Xu, Ruijie Hao, Tian Lv, Yingmin Lv, Zequn Zheng, Ming Sun, Le Luo, Ming Cai, Yike Gao, Junyi Wang, Ye Yin, Xun Xu, Tangren Cheng, Jun Wang. The genome of Prunus mume. Nature Communications, 2012; 3: 1318 DOI: 10.1038/ncomms2290

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/KXS6HDyZXdQ/121227142951.htm

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Backpacking Southeast Asia for 9 Months | soloflightEd

I resigned from my corporate job last January 2012 because I wanted to go on a long-term travel adventure. I was able to accomplish it by backpacking for nine months in seven countries in Southeast Asia.

Vietnam-Cambodia-Thailand-Indonesia-Singapore-Malaysia-Philippinesbackpacking soloflighted

I haven?t exhausted all the places in Southeast Asia which I could?ve done simply by hopping on a bus or riding a train. Laos and Myanmar were nearby countries that came to mind, but I was in no hurry.

The plan was simply to travel and bring my work while doing so and I have achieved this goal.

Backpacking Highlights

Here are some major highlights during that trip

Backpacking for nine months. It went to a point that I was already travelling from country to country as though I was travelling from town to town. I felt comfortable and I didn?t bother creating itineraries to visit a certain tourist spot. I?m too lazy a traveller to come up with day-to-day activities. I realized that slow travel works better for me.


Southeast Asia backpacking adventures

Acquiring this experience that it?s possible and not just another delusion makes me proud. Not that I didn?t have any problems along the way as there were few.

Issues on the Road

Loneliness wasn?t much of a big issue for me. There?s always the internet to keep me company. I also interacted with different people everyday and even if I didn?t, I was normally too busy online to even think that I needed somebody to talk to.

One of biggest concerns I had was money. After almost 6 months on the road, I was starting to worry where I was going to get the funds especially when they were depleting. My earnings laptop roadonline were sometimes not enough. Luckily, opportunities came by and these have proven to be miracles of which I am thankful for the instruments that have made me continue my journey.

Consequently, the reason why I was running out of money was because I satisfied my cravings for sleep. While other location-independent workers put more time and effort in launching businesses, I reverted to just finishing jobs on a basic level. Once I?ve met the minimum amount to send money home and enough for my basic needs, I stopped working. I just wanted to sleep all day and enjoy the stillness of things. I didn't maximize my full potential.

Towards the end of the trip, I realized that I only needed other channels to earn. It didn?t have to be just my online jobs, I could also earn by doing physical work. The summer job as a waiter in Malaysia was a perfect opportunity that also satisfied my desire to interact with people. I found out about other part-time jobs from then on.

More than the Travel

It?s a great feeling to have done this adventure because it made me realize a number of things I wouldn?t have fully understood had I still been in an office desk. Ultimately, I can say that it?s more than just travelling.

  • It?s about the quality of life and using a passion to ignite that burning desire to make the most out of living. Whether you want to live within a picket-fenced house, raising a family of your own; or be an accomplished corporate employee bent on climbing your way to the top. Whether you prefer living the simple life on a farm, or being a party animal where everybody is your friend. It?s your life. Build the desire and drive change.
  • It?s about showing that you have control over the situation.? Not to be led by others because you are capable of deciding that for yourself.? That even if there are obstacles and pit stops that prevent you from doing them today, when you have enough courage and plan to test it out, you?ll be amazed at what you can accomplish.
  • It?s how you become independent in making decisions by yourself and trusting your instincts rather than relying on others to make those calls.
  • It?s about DOING something and NOT letting anybody dictate how you SHOULD live your life just because they feel that they know better. Although you can consider thoughts and opinions from the concerned; in the end, it?s your decision because it is YOUR life and you deserve to be happy.

mui ne vietnam
White Sand Dunes - Mui Ne, Vietnam

What?s Next?

I?m preparing myself for other plans that need more attention. Time is gold and I don?t have much as of the moment. I may go back to the corporate world, or find other professions that will help me save more. This is for a better cause and for a bigger responsibility.

Still, I am thankful for having had the opportunity to travel to different places, experience adventures from a wanderer?s perspective, and live simply with what life has presented me. It?s given me a better outlook and I feel that I have a greater sense of direction.


Kuta Beach - Bali, Indonesia

This backpacking adventure is one of those experiences I?ll definitely tell my children in the future. I?m not closing doors on long-term travelling, I am simply postponing it for another time. Maybe by then, it will be more than just Southeast Asia. Maybe by then, I will tag a companion or two.

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This is my entry to the Pinoy Travel Blogger's Blog Carnival themed 2012: This Year In Travel which is hosted by Gay of PinayTravelJunkie.com. Click on the Blog Carnival Logo on the left to see more interesting posts and topics. Cheers to 2012!

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soloflightEd.com is a travel blog by Edcel Suyo. He enjoys performing headstands and crazy stunts during his trips in the Philippines and the rest of Asia. He just started his backpacking trip across Southeast Asia in order to live as a digital nomad. Read more about the beginning of his delusions of grandeur here.

For updates, Like his page on Facebook or Follow him on Twitter.
For questions, advertising, and other concerns, shoot an email to edblogs@yahoo.com.


Source: http://soloflighted.com/backpacking-southeast-asia-9-months/

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Spike Lee Makes Awesome NBA Ads [THE BRIEF] - Business Insider

Good morning, AdLand. Here's what you need to know today:

Spike Lee?starred and directed a new NBA commercial called "The King of New York," about Knicks legend Bernard King's 60-point game against the Nets on Christmas in 1984. Public Enemy's "Get Up Stand Up" provides a soundtrack for this Goodby Silverstein & Partners spot.

Get ready for more targeted television commercial with?Gracenote's?ad replacement system. It will premiere at CES.?

George Foreman Grills?is taking a new marketing approach. It has launched a $3 million campaign that uses a weight loss contest as a way to advertise the appliance.

Ad Age?looks at?what advertisers did wrong this year.

Here are five common?Facebook?marketing mistakes via All Facebook.

Previously on Business Insider Advertising:

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Tuesday, December 25, 2012

U.S. military officials investigating Navy SEAL's death as possible ...

This undated photo provided by the U.S. Navy shows Navy SEAL Cdr. Job W. Price. U.S. military officials are investigating the apparent suicide of Price, 42, of Pottstown, Pa., who died Saturday of a non-combat-related injury while supporting stability operations in Uruzgan Province, Afghanistan. (Photo by AP Photo/U.S. Navy)

WASHINGTON ? U.S. military officials are investigating the apparent suicide of a Navy SEAL commander in Afghanistan.

Navy SEAL Cdr. Job W. Price, 42, of Pottstown, Pa., died Saturday of a non-combat-related injury while supporting stability operations in Uruzgan Province, Afghanistan.

A U.S. military official said the death "appears to be the result of suicide." The official spoke on condition of anonymity because the death is still being investigated.

"The Naval Special Warfare family is deeply saddened by the loss of our teammate," said Capt. Robert Smith, Commander of Naval Special Warfare Group Two, which manages all Virginia-based Navy SEAL teams. "We extend our condolences, thoughts and prayers to the family, friends, and NSW community during this time of grieving."

"As we mourn the loss and honor the memory of our fallen teammate, those he served with will continue to carry out the mission," Smith added Sunday.

A U.S. military official confirmed Price was from Virginia Beach, Va.-based SEAL Team 4, which is part of the mission to train Afghan local police to stave off the Taliban in remote parts of Afghanistan. Price is survived by a wife and a daughter.

Source: http://www.nola.com/military/index.ssf/2012/12/us_military_officials_investig.html

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Monday, December 24, 2012

Free PLR eBooks Private Label Rights Downloads - Articles Droits ...

Private Label Articles - Get More Useful Content At Low Cost and Effort

Private label rights (PLR) are one of the hottest things in Internet marketing today. Everybody wants to know what they are and, more importantly, what benefits they can get out of them.

In essence, PLR is a kind of license you acquire for material, which allows you to change and edit existing material and call it your own. Without having to do a lot of work, you could be credited as the author of the material and not have to worry about any violations in copyright.

Not a lot of people know about the PLR articles, much less why they should pay attention to them. Give yourself the edge and find out why you should know all you can about PLR and how you can profit from them in the most efficient and effective way possible.

1. Saves time and effort.
You probably already know how much work and time it will take to write an article. On average, a single 700-word article will take about two hours to compose from scratch. If your intention is to create a website with over 50 pages, then you can see how daunting and time-consuming the task of simply writing content will be. PLR articles will save you this time and effort.

2. All credit goes to you.
You are under no obligation to credit the original author for PLR articles. As such, when you publish them on your website, no outbound links and advertisements will be there to distract your visitor / customer. All links will be focused on your brand and your affiliates.

3. Saves you money.
This point requires a different point from saving time and effort simply because of economics. Hiring writers to create content for your website averages about $15 per article. If your site were to hold even just 20 articles that you need to update regularly (say every two weeks), you'd see how the bill could add up.

But if you were to acquire PLR for a set of articles, you could save money because of the economics of scale. Articles are bought at bulk and as such it is possible to get your hands on 200 articles for only less than $30.

4. Editorial freedom.
You don't like how the article is written or the information it is presenting? PLR allows you to change the material right away without needing to ask permission from the writer.
This is also especially useful for optimizing your website for search engines since you can enrich the content with keyword phrases to improve your rankings in SERPs.

5. Create a brand for yourself.
Today, it's all about distinguishing yourself from the rest. PLR articles allow you to provide content that is both relevant and updated. By doing so you build a reputation with your target audience as an expert. And since people would much rather go with someone they trust, your chances of return visitors increases significantly.

6. Get professional results.
Many of the writers who offer articles with PLR are professionals and have access to the latest information regarding your field of interest. By acquiring the rights from them, you avail yourself of their professional results without having to retain their services regularly.

With one set of PLR articles and some creativity on your part, you can extend the life of the articles to the point where the content has more than paid for itself. So when sourcing out a supplier for PLR articles, ask for sample works to demonstrate the quality of articles you would be purchasing.

Now that you know why you should seriously consider getting PLR articles, here are some ways to get you started on profiting from them.

1. Compile a list or report.
You can consolidate a series of articles of a similar theme and package them as a report or listing of information. While you may think that anyone can do this, you'd be surprised how little of this is done.

Many people don't have the time to read or the willingness to read several articles at different times. Providing them a simplified version of the information they want will be a welcome offer for your visitors. You can either give away the report for free, sell it as your own product or use it as content on your website.

2. Use PLR content to create a series of small articles
This is especially useful when producing material for an email campaign. A series is by far, one of the more effective ways to create a following with your audience.

Give enough to allow them a feel for what you're offering and hint at giving more of the same if they will subscribe to your mailing list. In turn, your emails promote your website by inviting them to visit you on a more regular basis.

3. Produce ebooks.
It is very possible for you to take a set of PLR articles and come up with an ebook, for which you can credit yourself as the author.

Since you have created an entirely new product you could repackage this and sell this with your own resale rights. Just like you, there are people who are looking for material they can use for their own promotion needs so cater to this market as they are increasingly growing in number.

As you can see, using PLR articles are not only effective in providing truly useful content. They are also cost and labor-efficient, which means you can focus more of your time to more important matters, whether they are for business or otherwise.

Introducing the ultimate PLR articles pack, this massive PLR articles pack includes more than 200,000 PLR articles, all included with full private label right license. This massive PLR articles pack is categorized in more than 950 folders on different niche topics, from marketing articles to topics like health & fitness,pets,marketing,medical, fashion,travel, finance, birthdays, herbs and many many more.

This massive ultimate PLR articles pack is so huge that we had to divide them to several different packs, take a look below to see what is included in the massive 200,000 PLR articles pack.

Hello Friend,

If you would like to set up your own Info-Business, but hate to write, or have no idea where to get copy to create your own fresh products, then this is for you...

The "200,000 PLR Articles Package" is a huge collection of over 1,000,000 quality articles, all written by professional copywriters.

In other words: You'll be able to create a line of new niche products almost instantly!

Let me sum up what you'll get:

You'll receive over 200,000 high quality articles, each between 400 and 900 words. These cover some of the hottest subjects online...

You can do anything you want with this content...

Resell the articles as they are, create brand new Ebooks, special reports, eCourses or add them to your web site or newsletters.

Source: http://articulosdesociedad.blogspot.com/2012/12/free-plr-ebooks-private-label-rights.html

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Juicing Counseling That Will Increase Your ? ? Critical Care 2011 ...

If you want to really give your diet plan a wholesome boost, try generating your own personal good tasty juices back at home. It is spend each of the fruits and vegetables that you just love and switch them into tasty, nourishing tasty juices. If you?re not sure how to start, this short article will show you how.When starting to juice it?s best to start slow. Use only flavours you know you already like, and don?t try new things until finally you know you are ready. Begin by combining consumers new flavours, like wheatgrass, into fruit you?ve already been boozing. In no time possible proceed to positive quality recipes!

When presenting new produce in your juicing routine, try and include only one new organic at a time. When you don?t handle a specific ingredient properly, you will be aware what induced it.

Website

Drinking good fruit and veggies is among the most effective actions you can take to improve your wellbeing and health related. When starting to incorporate juicing in to your way of life it is important that you investigation the health rewards derived from several types of fruits and vegetables to enable you to make the most efficient tasty juices to get your certain health and fitness wants and needs. This article has a variety of great juicing guidelines.

Ginger is undoubtedly an amazing food items which will help relieve gastrointestinal upset. Making juices with ginger is the best way to boost your wellness, in addition provide a kick of taste. Since ginger will help minimize swelling, it?s helpful for dealing with acid reflux, in addition to ulcers and upset stomachs.

Understand that all fruit have different qualities and act in a different way when being juiced. You may need a specific equipment to extract juice from citrus berry, such as oranges and grapefruits. Use attention when juicing melons melon juice usually likes bad when juiced with some other fruit.

Website

Receive the ripest apples you can get if you want to make apple juice. When bruised apples also deliver good juice, you must still minimize aside the bruised places. A number of types of apples, such as the ones that are sweeter in taste, usually make the richest, most flavorful juices. These apples include Gala, Fuji, Red Delightful, and Rome apples.

Geared up your greens regarding for juicing. Definitely is necessary should you have a hectic living. Geared up your greens in the morning or the previous night for each day?s juice whilst keeping them inside the fridge. That way, when you spare the time to make your juice, the greens are ready to go.

Masticating juicers are a wonderful kind of juicer so long as you are trying to find out what type of juicer is the ideal choice. Masticating juicers are mild and make juice with no eliminating or removing practical nutrients inside fruits and vegetables. This too aids to the juice preserve good much longer.

New juice may possibly taste somewhat bitter, but this could be masked by having in wonderful fruits and veggies. Oranges, strawberries and carrots impart wonderful and unique variants. Probably the most well-known quality recipes calls for cherries and a combination of unique berries. Build your own batch of juice tailored to suit your own likes.

You should juice your greens if you?re not the greatest of cooks. Juicing greens will help you to get the nutrients from them without needing to do any substantial to have. Juicing is a straightforward, fast and efficient method to get each of the practical nutrients that greens have to offer with no suffering from the hassle of truly cooking them.

Website

To get a a lot more flavorful organic juice, consider including a little bit of ginger. Ginger gives an exclusive taste to juices and may even cover in the strong taste of some produce. Ginger provides many health and fitness benefits, such as stopping atherosclerosis and decreasing blood pressure levels.

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Martha Raddatz

Do You Know How To Effectively Communicate to Your Copywriter ...

In addition to trust, the most critical factor in creating a successful client / copywriter relationship is the same as in creating any other relationship . . .

Good communication.

You and your copywriter need to clarify your expectations of each other, preferably in writing. Each of you needs to understand the other?s expectations. Your writer also needs to know the audience and purpose of what he or she will be writing. You can?t just say, ?I need a squeeze page and four blog posts by next Tuesday.?

You need to clearly express . . .

Who the target audience is. The more information, the better.
What the articles and blogs need to say?topics covered, length, and formal or informal style.
Where the blogs and articles will appear. The writer can visit those sites to get a feel for the style and tone of the writing.
When you need the writing completed. Allow for editing time.
Why the articles and blogs are being written and what the calls to action need to be.
How the writing will be used, such as adding articles to a directory, compiling an ebook, or guest blogging.

Your copywriter needs to ensure you?re aware of his or her guidelines and best practices for . . .

Writing the copy. How does he or she plan to write those articles and blogs and create effective calls to action?
Managing deadlines. If you?re both communicating, there should be no issues here. When you have a big project, setting internal deadlines is crucial so no one is scrambling at the last minute.
Editing. Some copywriters have their own editors, and some do not.
Gathering background information. How much research will you provide, and how much will your copywriter need to do?
Revising copy. If the copy doesn?t speak to the audience or isn?t well done, you need to know how the copywriter will make it right. However, there should also be a guideline for what happens if?you accidentally misinform the writer or provide inaccurate research.
Requesting payment.Are you paying your copywriter by the project, by the hour, or some other arrangement? When does the writer invoice, and how long do you have to pay after invoicing?

Many of these points can and should be put in the master contract you have with your copywriter, as they?ll be constant, but others will vary by project. Always put as much in writing as you can, even if it?s just an email. Written communication helps projects run more smoothly.

As you work with your copywriter, you?ll get to know each other and how you work best. For example, my copy is significantly better if I have at least two days?as opposed to a rush job?because I write the first draft, let it sit overnight, and then go back and polish. So rush projects are kept to a minimum.

A good client / copywriter relationship can be a gold mine for you. Nurture it. You?ll be surprised how a good writer can make your life easier and your business more lucrative.

?

Discover simple marketing strategies to attract and convert prospects. My bimonthly ezine, Sumer?s Secrets is packed with tips on how to improve your web copy, promote your website, and market your brand.? Sign up and receive a FREE report on creating web copy that will increase sales and site traffic.

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Source: http://www.youthrapidresponse.org/681-do-you-know-how-to-effectively-communicate-to-your-copywriter.html

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Saturday, December 22, 2012

Luca di Montezemolo wants Sebastian Vettel in Ferrari ? Formula 1 ...

Luca di Montezemolo wants Sebastian Vettel in Ferrari ? Formula 1 news

Ferrari president Luca di Montezemolo has said that he wants the three-time world champion, Sebastian Vettel in his team in the future.

Red Bull Racing driver, Vettel has successfully claimed his third consecutive championship title in this season. Although, he had a very tough competition with Fernando Alonso of Ferrari, but he performed impressively well in the last few races and successfully won the title by just three points from the Spaniard.

Montezemolo has recently said that they have an eye on the veteran German driver and may take him as their race driver in the future. However, he insisted that they will only take Vettel into their team if Alonso was to leave for some reason as they can?t have two dominating drivers at the same time.

?Vettel is a future potential Ferrari driver,? Montezemolo told Auto Motor and Sport. ?If Alonso was to retire tomorrow, for whatever reason, then I want Vettel.?

Nonetheless, he praised the performance of Alonso who fought exceptionally well in this season even with an uncompetitive car. Additionally, he said that he is really happy with the two-time world champion who is more than just a driver.

?I?m incredibly happy with him,? Montezemolo agreed. ?He is more than just a driver.?

In addition, he said that it is very difficult to have Alonso and Vettel in the team at the same time.

?Alonso and Vettel, that would be difficult,? he said. ?When you have the best driver in the world, you must offer optimal conditions.?

Besides, he said that Michael Schumacher told him about Vettel when he was very young and asserted that the seven-time world champion was right about his compatriot.

?He?s young,? Montezemolo started, ?he has his feet on the floor, and he has an indomitable will to win. Schumacher made me aware of him years ago because he knew him from his karting years. I must say, Michael was right.?

The Italian team is the oldest and the most successful team in the sport and it will be very exciting to see the youngest triple world champion behind the wheel of Ferrari car in the future.

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Source: http://blogs.bettor.com/Luca-di-Montezemolo-wants-Sebastian-Vettel-in-Ferrari-Formula-1-news-a210277

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